Science & Justice
Volume 49, Issue 2 , Pages 94-101 , June 2009

Comparative analysis of 1-phenyl-2-propanone (P2P), an amphetamine-type stimulant precursor, using stable isotope ratio mass spectrometry: Presented in part as a poster at the 2nd meeting of the Joint European Stable Isotope User Meeting (JESIUM), Giens, France, September 2008

  • S. Schneiders

      Affiliations

    • Bundeskriminalamt (Federal Criminal Police Office), Forensic Science Institute, Unit Central Analytics II (KT 12), D-65173 Wiesbaden, Germany
    • Corresponding Author InformationCorresponding author. Tel.: +49 6115517095; fax: +49 6115514348.
    • ,
  • T. Holdermann

      Affiliations

    • Bundeskriminalamt (Federal Criminal Police Office), Forensic Science Institute, Unit Central Analytics II (KT 12), D-65173 Wiesbaden, Germany
    • ,
  • R. Dahlenburg

      Affiliations

    • Unit Toxicology (KT 34), Forensic Science Institute, D-65173 Wiesbaden, Germany

Received 16 December 2008 ,Revised 4 March 2009 ,Accepted 5 March 2009.

References 

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  2. Personal communication”, Joint Customs/Police Precursor Monitoring Unit at the BKA, 2008.
  3. Precursors and Chemicals Frequently Used in the Illicit Manufacture of Narcotic Drugs and Psychotropic Substances: Report of the International Narcotics Control Board for 2007 on the Implementation of Article 12 of the United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances of 1988 (E/INCB/2007/4), date of publication: 5th March 2008 www.incb.org/incb/precursors_reports.html
  4. United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances of 1988, Regulations EC No. 273/2004; of 11th February 2004 EC No. 111/2005 of 22th December 2004 and EC No. 1277/2005 of 27th July 2005.
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  6. Forbes IJ, Kirkbride KP. The origin of alkenes in illicit amphetamine: an examination of the illicit synthesis of phenyl-2-propanone. J. Forensic Sci. 1992;37:1311–1318
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  8. Carter JF, Titterton EL, Grant H, Sleeman R. Isotopic changes during the synthesis of amphetamines. Chem. Commun. 2002;2590–2591
  9. Carter JF, Titterton EL, Murray M, Sleeman R. Isotopic characterisation of 3,4-methylendioxyamphetamine and 3,4-methylendioxyamphetamine (ecstasy). Analyst. 2002;127:830–833
  10. Palhol F, Lamoureux C, Naulet N. 15N isotopic analyses: a powerful tool to establish links between seized 3, 4-methylendioxymethamphetamine (MDMA) tablets. Anal. Bioanal. Chem. 2003;376:486–490
  11. Buchanan HS, Nic Daeid N, Meier-Augenstein W, Kemp HF, Kerr WJ, Middleditch M. Emerging use of isotope ratio mass spectrometry as a tool for discrimination of 3,4-methylendioxymehamphetamine by synthetic route. Anal. Chem. 2008;80(9):3350–3356
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  13. Ehleringer JR, Cerling TE, West JB. Forensic science applications of stable isotope ratio analysis. In:  Blackledge RD editors. Forensic Science on the cutting edge: New methods for trace evidence analysis. Hoboken, New Jersey, USA: John Wiley & Sons, Inc.; 2007;p. 399–422
  14. Meier-Augenstein W, Fraser I. Forensic isotope analysis leads to identification of a mutilated murder victim. Sci. Justice. 2008;48:153–159
  15. Serra F, Janeiro A, Calderone G, Moreno Rojas JM, Rhodes C, Gonthier LA, et al. Inter-laboratory comparison of elemental analysis and gas chromatography combustion isotope ratio mass spectrometry (GC-C–IRMS). Part I: δ13C measurements of selected compounds for the development of an isotopic Grob-test. J. Mass Spectrom. 2007;42:361–369
  16. Bilke S, Mosandl A. Measurements by gas chromatography/pyrolysis/mass spectrometry: fundamental conditions in 2H/1H isotope ratio analysis. Rapid Commun. Mass Spectrom. 2002;16:468–472
  17. J. Jung, Isotopendiskriminierung und Enantioselektivität–Basis der Authentizitätsbewertung biogener Stoffe (Isotopic discrimination and enantio selectivity–basis for the authenticity assessment of biogenic substances), PhD thesis, University of Frankfurt, Institute of Food Chemistry: Der andere Verlag, Tönning, Germany, 2006, pp 60, ISBN 3-89959-507-6.
  18. Aitken C, Taroni F. In: Statistics and the Evaluation of Evidence for Forensic Scientists. Second Edition. Chichester, England: John Wiley & Sons, Ltd.; 2004;p. 359
  19. Ruff C, Hör K, Weckerle B, Schreier P. 2H/1H ratio analysis of flavor compounds by on-line gas chromatography pyrolysis isotope ratio mass spectrometry (HRGC-P–IRMS): benzaldehyde. J. High Resol. Chromatogr. 2000;23:357–359
  20. Culp RA, Noakes JE. Identification of isotopically manipulated cinnamic aldehyde and benzaldehyde. J. Agric. Food Chem. 1990;38:1249–1255
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PII: S1355-0306(09)00054-9

doi: 10.1016/j.scijus.2009.03.001

Science & Justice
Volume 49, Issue 2 , Pages 94-101 , June 2009

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